Monday, December 5, 2011

Senescent bacteria as potential live vaccines


In 2008, I submitted a project to the Round 2 of Grand Challenges Exploration funded by Bill and Melinda Gates Foundation. This was one of the projects selected by the reviewers amongst 3000 application received by them. However, it failed to obtain funding after the due diligent process, the most probable reason being the lack of affiliation with any research institutes at the time.

In this project, I had made an assumption. i.e. the small colony variants obtained after incubating with sub-inhibitory concentrations of aminoglycosides are senescent bacteria (discussed previously).

The project can be read at https://docs.google.com/viewer?a=v&pid=explorer&chrome=true&srcid=0B0-RiF-cW8KcNGJiOWMxNzUtMzdlYy00MzVlLThiOTUtOGY1Y2RmMWFiZTI4&hl=en_US

Till now, the project has not been tested.

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